Products for Use Against C. difficile

Cleaning & Disinfecting

It is important to clean surfaces potentially contaminated with C. diff before disinfecting. The CDC recommends use of a disinfectant that is registered with the Environmental Protection Agency (EPA) and is effective against C. difficile (see EPA List K).12 It is important to follow the directions for use, including applying the product for the correct contact time. Specifically, the CDC recommends:

Clorox Healthcare Product Recommendations

The following Clorox Healthcare® cleaner disinfectants can be used to effectively manage C. difficile on environmental surfaces and equipment in healthcare settings:

Cleaning & Disinfecting

It is important to clean surfaces potentially contaminated with C. diff before disinfecting. The CDC recommends use of a disinfectant that is registered with the Environmental Protection Agency (EPA) and is effective against C. difficile (see EPA List K).12 It is important to follow the directions for use, including applying the product for the correct contact time. Specifically, the CDC recommends:

Clorox Healthcare Product Recommendations

The following Clorox Healthcare® cleaner disinfectants can be used to effectively manage C. difficile on environmental surfaces and equipment in healthcare settings:

Germicidal Wipes
EPA Reg. No. 67619-12
5″ x 6″ Clinical Wipes, 6/150 ct., Item No. 30577
6.75″ x 9″ Multi-purpose Wipes, 6/70 ct., Item No. 35309
6.75″ x 9″ Multi-purpose Wipes, 6/100 ct., Item No. 32621
12″ x 12″ Terminal Wipes, 2/110 ct., Item No. 30358
12″ x 12″ Terminal Wipes Refill, 2/110 ct., Item No. 30359
Germicidal Cleaners
EPA Reg. No. 56392-7
6/32 fl. oz. Spray, Item No. 68970
6/32 fl. oz. Pull-Top, Item No. 68832
4/128 fl. oz. Refill, Item No. 68978
Fuzion®
EPA Reg. No. 67619-30
9/32 fl. oz. Spray, Item No. 31478
Clorox Healthcare® Spore Defense® Cleaner Disinfectant
EPA Reg. No. 67619-40
4/128 fl. oz., Item No. 32122
4/128 fl. oz., Item No. 32409
Hospital Cleaner Disinfectant Towels with Bleach
EPA Reg. No. 56392-8
6.75″ x 9″ Multi-purpose Wipes, 6/70 ct., Item No. 35309

References

1. Mayo Clinic. C. difficile infection http://www.msn.com/en-us/health/medical/c-difficile-infection/ar-AA10kZS6?li=BBnba9O (accessed Aug 11, 2022).
2. Centers for Disease Control and Prevention (CDC). C. diff (Clostridioides difficile) http://www.cdc.gov/cdiff/index.html (accessed Aug 11, 2022).
3. Centers for Disease Control and Prevention (CDC). FAQs for Clinicians about C. diff http://www.cdc.gov/cdiff/clinicians/faq.html#what-is (accessed Aug 11, 2022).
4. Paredes-Sabja, D.; Shen, A.; Sorg, J. A. Clostridium Difficile Spore Biology: Sporulation, Germination, and Spore Structural Proteins. Trends Microbiol. 2014, 22 (7), 406–416. http://doi.org/10.1016/J.TIM.2014.04.003.
5. Johns Hopkins Medicine. Toxic Megacolon http://www.hopkinsmedicine.org/health/conditions-and-diseases/toxic-megacolon (accessed Aug 11, 2022).
6. Surgical management of Clostridioides (formerly Clostridium) difficile colitis in adults http://www.uptodate.com/contents/surgical-management-of-clostridioides-formerly-clostridium-difficile-colitis-in-adults (accessed Aug 11, 2022).
7. Centers for Disease Control and Prevention. What is C. diff? http://www.cdc.gov/cdiff/what-is.html (accessed Aug 11, 2022).
8. Centers for Disease Control and Prevention. FAQs for Clinicians about C. diff http://www.cdc.gov/cdiff/clinicians/faq.html (accessed Aug 11, 2022).
9. Kramer, A.; Schwebke, I.; Kampf, G. How Long Do Nosocomial Pathogens Persist on Inanimate Surfaces? A Systematic Review. BMC Infect. Dis. 2006, 6. http://doi.org/10.1186/1471-2334-6-130.
10. Guh, A. Y.; Mu, Y.; Winston, L. G.; Johnston, H.; Olson, D.; Farley, M. M.; Wilson, L. E.; Holzbauer, S. M.; Phipps, E. C.; Dumyati, G. K.; Beldavs, Z. G.; Kainer, M. A.; Karlsson, M.; Gerding, D. N.; McDonald, L. C. Trends in U.S. Burden of Clostridioides Difficile Infection and Outcomes . N. Engl. J. Med. 2020, 382 (14), 1320–1330. http://doi.org/10.1056/NEJMOA1910215/SUPPL_FILE/NEJMOA1910215_DISCLOSURES.PDF.
11. Association for Professionals in Infection Control and Epidemiology. Antimicrobial stewardship http://apic.org/professional-practice/practice-resources/antimicrobial-stewardship/ (accessed Aug 11, 2022).
12. Environmental Protection Agency. List K: EPA’s Registered Antimicrobial Products Effective against Clostridium difficile Spores http://www.epa.gov/pesticide-registration/list-k-epas-registered-antimicrobial-products-effective-against-clostridium (accessed Aug 11, 2022).

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